Dynamics of Changes in Bone Densitometric Parameters and the pH Level of Oral Fluid Among Children with Juvenile Idiopathic Arthritis During the Use of Developed Treatment and Prevention Complex
DOI:
https://doi.org/10.53933/sspmpm.v3i2.91Keywords:
juvenile idiopathic arthritis, densitometry, drugs, toothpaste, pharmacotherapy, treatment and prevention complex, multidisciplinary studiesAbstract
Prevention and treatment of major dental diseases among children with juvenile idiopathic arthritis is quite a difficult task. It is necessary to develop appropriate therapeutic and preventive measures, taking into account the pathogenetic factors and peculiarities of such somatics. Among fifty-five children with juvenile idiopathic arthritis aged 6-10 years, the main densitometric parameters of bones were determined and the pH stability of the oral fluid was assessed against the background of the use of the developed treatment and prevention complex, which includes modern, effective, safe, and affordable medicines.
As a result, after a year of using the treatment and prophylactic complex, an improvement in the densitometric indicators of bone tissue was observed among children, which indicated an improvement in their mineralization and structure, as well as a normalization of functional adaptation and compensatory reactions in the body, which maintain the stability of the pH of the oral fluid.
References
Giancane G, Alongi A, Ravelli A. Update on the pathogenesis and treatment of juvenile idiopathic arthritis. Curr Opin Rheumatol. 2017. No 29(5). P. 523‐529. DOI: 10.1097/BOR.0000000000000417. DOI: https://doi.org/10.1097/BOR.0000000000000417
Prakken B, Albani S, Martini A. Juvenile idiopathic arthritis. Lancet. 2011. 377(9783). P. 2138‐2149. DOI: 10.1016/S0140-6736(11)60244-4. DOI: https://doi.org/10.1016/S0140-6736(11)60244-4
Marushko T.V. Juvenile idiopathic arthritis. Pediatrics. No. 1 (44). March. P. 39-41 URL: https://health-ua.com/article/36210-yuvenlnij-dopatichnij-artrit.
Revenko I.V., Anikeeva T.V. Symptoms of rheumatoid arthritis and other arthritis. Diagnosis and treatment. Dobrobut. 03.04.2020. URL https://www.dobrobut.com/ua/med/c- simptomy-revmatoidnogo-artrita-i-drugih-artritov-diagnostika-i-lecenie.
Jus M.B. Quality of life and long-term outcomes in young and adult patients with juvenile rheumatoid arthritis in Ukraine. Acta medica Leopoliensia. 2017. Is. 23. No. 4. P. 4-11. DOI: https://doi.org/10.25040/aml2017.04.004
Glazunov O.A., Fesenko D.V. Modern views on the relationship between periodontal disease and rheumatoid arthritis. Bulletin of Dentistry. 2018. No. 3 (104). P. 82-88.
Pylypyuk O.Y., Kuligina V.M., Shinkaruk-Dykovytska M.M. et al. Results of clinical dental examination of prepubescent and pubescent children with juvenile rheumatoid arthritis. Herald of problems of biology and medicine. 2020. Is. 4 (158). P. 365-369. URL: https://dspace.vnmu.edu.ua/bitstream/handle/123456789/6084/77- min.pdf?sequence=1&isAllowed=y. DOI: https://doi.org/10.29254/2077-4214-2020-4-158-365-369
Boyko Y.E. Modern treatment of juvenile rheumatoid arthritis: the era of biological therapy.
Rational pharmacotherapy. 2012. No. 1 (22). P. 38-48
https://rpht.com.ua/ua/archive/2012/1%2822%29/pages-38-48/suchasne-likuvannya-yuvenilnogo- revmatoyidnogo-artritu-era-biologichnoyi-terapiyi.
Kobus A., Kierklo A., Sielicka D. Et al. Młodzieńcze idiopatyczne zapalenie stawów a stan jamy ustnej [Juvenile idiopathic arthritis and oral health]. Postepy Hig Med Dosw (Online). 2016. No. 70. Р. 410‐419. Published 2016 May 4. DOI: 10.5604/17322693.1201119. DOI: https://doi.org/10.5604/17322693.1201119
Barut K., Adrovic A., Şahin S. et al. Juvenile Idiopathic Arthritis. Balkan. Med. J. 2017. No 34(2). Р. 90‐101. DOI: 10.4274/balkanmedj.2017.0111/. URL: https://pubmed.ncbi.nlm.nih.gov/28418334/. DOI: https://doi.org/10.4274/balkanmedj.2017.0111
FARMA Sonost 2000. User’s manual. Seoul, Corea: Strumentazione Medicale. 2017. 70 s. URL: https://www.wellstore.it/media/productattach/m/a/man_sonost_2000.pdf.
Dorosh I.V., Denga E.M., Denga A.E. et al. Biophysical parameters of periodontal tissues and bone quality index in children with juvenile rheumatoid arthritis during complex dental treatment. DOI: 10.24412/2520-6990-2021-26113-39-44.
Denga O.V., Denga E.M., Levitsky A.P. Informativeness of pH-test of saliva during sanation-prophylactic functional reactions in the oral cavity in children. Bulletin of Dentistry. 1995. No. 1. P. 42-45
Dienga O.V., Dienga E.M., Dienga A.E. Patent of Ukraine 47093, IPC (2009) G01N 33/487. Method of predicting dental diseases. Published 11.01.10, Bul. No. 1.
Hayduchok I., Shapovalov V. Forensic pharmacy and medicine: risks for pharmacotherapy of addiction and countering of illegal circulation of psychoactive substances in the COVID-19 pandemic. 2021. SSP Modern Pharmacy and Medicine. Vol.1. N.2. P.1-28. URL: https://DOI.org/10.53933/sspmpm.v1i2.32. DOI: https://doi.org/10.53933/sspmpm.v1i2.32
Hayduchok I., Shapovalova V., Ishcheikin K. et al. Pharmaeconomic approaches for pharmacotherapy of Rheumatoid arthritis. Likars’ka Sprava. 2021. No. 1–2. P.70-79.
https://doi.org/10.31640/JVD.1-2.2021(11). URL: DOI: https://doi.org/10.31640/JVD.1-2.2021(11)
https://liksprava.com/index.php/journal/article/view/463.
Shapovalova V. Forensic and pharmaceutical risks in the organization of pharmacotherapy of covid, post-covid and long-covid disorders. COVID-19 and vaccination practice standards. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 4. P.1–24. URL: https://doi.org/10.53933/sspmpm.v2i4.69. DOI: https://doi.org/10.53933/sspmpm.v2i4.69
Hayduchok І., Shapovalov V. Covid-19: multidisciplinary researches of forensic and pharmaceutical risks and causal relationships of unqualified medical care for patients during pandemic. 2022. SSP Modern Law and Practice. Vol.2. N.1. P.1-25. URL: https://DOI.org/10.53933/sspmlp.v2i1.39. DOI: https://doi.org/10.53933/sspmlp.v2i4.74
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Tetyana Pyndus, Volodymyr Pyndus, Iryna Dorosh, Nadiia Malekh
This work is licensed under a Creative Commons Attribution 4.0 International License.