The peculiarities of the functional state of endocrinal system in patients with different epilepsy types
DOI:
https://doi.org/10.53933/sspmpm.v1i1.9Keywords:
epilepsy, estrogenes, progesterone, testosteroneAbstract
In the article the data about the content of estradiol, progesterone and testosterone were determined in patients with epilepsy in the period between seizures. These results show the changes of the functional state of hypophysis-gonad system in epileptics. It was shown that in women decreasing concentration of progesterone was noted and increasing of the level of estrogenes was noted too, at the background of the nomal content of testosterone. These data were expressed in the 2 phase of the menstrual cycle. In men with epilepsy in the period between attacks increasing of general testosterone was marked.
References
Badaljan L.O., Temin P.A., Muhin K.Ju., Semenov P.A. Nejrojendokrinnye narushenija pri jepilepsii i ih gormonal'naja korrekcija (Obzor) // Sov. medicina.- 1989.- № 10.- S. 49-51.
Badaljan L.O., Temin P.A., Muhin K.Ju. Gormonal'no-obmennye projavlenija jepilepsii: diagnostika i lechenie: Metod. Rekomendacii. MZ SSSR. Moskva.- 1991.- 18 s.
Badaljan L.O., Temin P.A., Ametov A.S., Muhin K.Ju. Diskussionnye voprosy problemy menstrual'noj jepilepsii // Zhurnal nevropat. i psih. im. S. S. Korsakova.- 1998.- Vyp. 6.- S. 120-123.
Vlasov P.N. Katamenial'naja jepilepsija: klinicheskie, jelektrojencefalograficheskie, gormonal'nye i terapevticheskie aspekty // Avtoref. dis. kand. med. nauk.- Moskva.- 1993.- 20 s.Backtrom T. Epilepsy in women. Estrogen and progesterone plasma levels // Experiment.- 1976.- Vol. 32, № 2.- P. 248 – 249. DOI: https://doi.org/10.1007/BF01937792
Bonicelli U., Melis G. B., Paoletti A. M. Unbalanced progesterone and estradiol secretion in catamenial epilepsy // Epilepsy.- 1989.- Vol. 3.- P. 100 – 106 DOI: https://doi.org/10.1016/0920-1211(89)90037-5
Herzog A.G., Russell V., Vaitukaitis J.L., Gerschwind N. Neuroendocrine dysfunction in temporal lobe epilepsy // Arch. Neurol.- 1982.- V. 39, № 3.- P. 133 - 135. DOI: https://doi.org/10.1001/archneur.1982.00510150003001
Murri L., Bonucelli U., Melis G. B. Neuroendocrine evaluation in catamenial epilepsy // Funct. Neurol.- 1986.- V. 1, № 4.- P. 399 - 403.
Mirotvorskaja G.N., Poljakova N.B., Hohlova V.A. Gistohimicheskie izmenenija v jadrah perednego gipotalamusa pri jeksperimental'nom sudorozhnom pristupe // Jepilepsija (klinika, patogenez, lechenie).- Moskva, 1982.- S. 388 – 391.
Rybnikova E.A., Rakickaja V.V., Shaljapina V.G. Uchastie striatuma v central'noj reguljacii gormonal'noj funkcii gonad // Ros. fiziol. zhurnal.- 1999.- T. 85, № 4.- S. 594-597.Fountain N. B., Bear Jonathan Responses of deep entorhinal cortex are epileptiform in an electrogenic rat model of chronic temporal lobe epilepsy // J. Neurophysiol.- 1998.- Vol. 80, № 1.- P. 230-240. DOI: https://doi.org/10.1152/jn.1998.80.1.230
Amado D., Cavalherio E., Bentivoglio M. Epilepsy and hormonal regulation: the patterns of GnRH and galanin immunoreactivity in the hypothalamus of epileptic female rats // Epilepsy Res.- 1993.- № 14.- P. 149-159. DOI: https://doi.org/10.1016/0920-1211(93)90019-4
Weiland N.G. Estradiol selective regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus // Endocrinology. - 2003.- Vol. 131, № 2.- P. 662-668. DOI: https://doi.org/10.1210/endo.131.2.1353442
Krester D.M., McLachlan R.I., Robertson D.M. Control of spermatogenesis by follicle stimulating hormone and testosterone // Clinical Endocrinology and metabolisms. - 1992.- Vol. 6.- P. 335-354. DOI: https://doi.org/10.1016/S0950-351X(05)80153-3
Jendokrinologija i metabolizm / Pod red. D.D. Baktera, A.E. Brodusa.- M.: Medicina, 1985.- 459 s. Zimmerman A.W. Hormones and epilepsy // Neurol. Clin. - 1986.- Vol. 4, № 4.- Р. 853-861. DOI: https://doi.org/10.1016/S0733-8619(18)30951-4
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