Research of Acute Toxicity and Anti-Inflammatory Activity of Extracts of Eryngium Planum
DOI:
https://doi.org/10.53933/sspmpm.v2i1.36Keywords:
eryngium, apiaceae, medicinal plants, anti-inflammatory actionAbstract
Most pathological processes in the human body of various origins are accompanied by signs of inflammation, namely: swelling (tumor), redness (rubor), fever (calor), pain (dolor) and dysfunction of a particular organ or system (functio laesa). The pathological process of inflammation is a response to the action of external or internal phlogogenic agents. Today, nonsteroidal anti-inflammatory drugs are the main drugs for the treatment of inflammatory processes. Therefore, one of the key tasks of pharmacy is the development and research of herbal anti-inflammatory drugs. One of the promising plants that has anti-inflammatory action is Eryngium planum. These are plants that belong to the family Apiaceae (Umbelliferae) and contain a large number of biologically active substances.
References
Zaiko M., Byts Yu., Myslytskyi V. Patofiziolohiia. 4-te vyd. Kyiv: Medytsyna. 2014; 752 s.
Kalenichenko H., Maloshtan L., Shatalova O. Doslidzhennia mekhanizmu protyzapalnoi dii hustoho ekstraktu z lystia lishchyny zvychainoi. 2015.Ukrainskyi biofarmatsevtychnyi zhurnal.Vol.1.N.6. P.30-33.
Hrytsyk R., Kireev I., Struk O., Klymenko A. Doslidzhennia protyzapalnoi aktyvnosti ekstraktiv polynu hirkoho ta polynu zvychainoho za umovy patolohii riznoho henezu. 2020. Medical and Clinical Chemistry. Vol. N. 2. P. 87-93. URL: https://doi.org/10.11603/mcch.2410-681x.2020.v.i2.11365. DOI: https://doi.org/10.11603/mcch.2410-681X.2020.v.i2.11365
The Plant List. Royal Botanic Gardens, Kew and Missouri Botanical Garden. 2021. URL: http://www.theplantlist.org/.
IPNI. International Plant Names Index. The Royal Botanic Gardens, Kew, Harvard University Herbaria & Libraries and Australian National Botanic Gardens. 2021. URL: http://www.ipni.org/.
Hrodzinskyi A. Likarski roslyny: entsyklopedychnyi dovidnyk. Kyiv: «Ukrainska entsyklopediia» im. M. P. Bazhana; 1992. 544 s.
Grytsyk А., Gnatoyko К. Characteristics of plants of the genus eryngium and prospects of their use in medicine. 2021. SSP Modern Pharmacy and Medicine. Vol.1. N.2. P.1-8. URL: https://doi.org/10.53933/sspmpm.v1i2.27. DOI: https://doi.org/10.53933/sspmpm.v1i2.28
Stephanov О.V. Doklinichni doslidzhennia likarskykh zasobiv: metodychni rekomendatsii. Preclinical research of drugs: methodical recommendations. 2001. Кyiv: Avitsena. 339 s.
European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (ETS No. 123). Strasbourg, 18.III.1986. Council of Europe. URL: https://rm.coe.int/168007a67b.
Zakon Ukrainy “Pro zakhyst tvaryn vid zhorstokoho povodzhennia” vid 08.11.2021. Verkovna Rada of Ukraine. URL: https://zakon.rada.gov.ua/laws/show/3447-15.
Verkhovodova Yu., Kireiev I., Koshovyi O. Vyvchennia hostroi toksychnosti vpershe otrymanykh ekstraktiv shavlii likarskoi. 2019. Art of Medicine. Vol.1. N.2. P.20-24.
Puda V.P., Fira L.S., Lykhatskyi P.H. Vyvchennia protyzapalnoi aktyvnosti sukhoho ekstraktu z lystia salatu posivnoho. 2018. Medical and Clinical Chemistry. Vol.1. N.3. P.57-62. URL: https://doi.org/10.11603/mcch.2410-681x.2018.v0.i3.9566. DOI: https://doi.org/10.11603/mcch.2410-681X.2018.v0.i3.9566
Ataman O. Patofiziolohiia. Vinnytsia. Nova knyha; 2012. 448 s.
Shchokina K, Drohovoz S., Maksymov Yu. Porivniannia protyeksudatyvnoi dii suchasnykh nesteroidnykh protyzapalnykh zasobiv. 2004. Liky. N.3-4. P. 34-40.
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