Calendula Officinalis L.: Study for Prospects of Creating Combined Dosage Forms with Naturally Similar Properties
DOI:
https://doi.org/10.53933/sspmpm.v5i1.175Keywords:
calendula officinalis, biologically active substances, combined dosage formsAbstract
Calendula officinalis L. is a part of almost 200 dosage forms. Despite the long tradition of use, the genus has not been properly studied. Pharmacological studies show that C. officinalis exhibits antibacterial, antiviral, anti-inflammatory, antitumor and antioxidant properties. A multidisciplinary and comprehensive study of calendula (Calendula officinalis L.) and a review of several medicinal plant raw materials with a similar content of biologically active substances were conducted for the prospects of creating combined dosage forms with naturally similar properties based on them. As well as a study of medicinal plant raw materials with a similar composition of biologically active substances. A review of the literature showed that quite a few drugs with different pharmacological effects have been created from the raw material of calendula officinalis, such as Gastrofit, calendula tincture, calendula ointment, Clotrex, Bronhofit, Ugrin®, Phytodent®, Rotokan, Tazalok™ and others. The task was set to create combined drugs, combined dosage forms with naturally similar properties using analogues of chemical-pharmaceutical origin (synthesis) of known pharmacological substances (active pharmaceutical ingredients), as well as medicinal plant raw materials using the example of raw materials of calendula flowers, hemp flowers, their introduction into industrial pharmaceutical production and medical practice, or individual manufacture according to a doctor's prescription in pharmacies while ensuring their quality, safety, effectiveness and economic availability.
References
The European Medicines Agency. Who we are. EMA. 2025. URL: https://www.ema.europa.eu/en/about-us/who-we-are
European Union monographs and list entries. ЕМА. 2025. URL: https://www.ema.europa.eu/en/human-regulatory-overview/herbal-medicinal-products/european-union-monographs-list-entries
Fialová S.B., Rendeková К., Mučaji P. et al. Context of Skin and Wound Infections, Considering European Legislation and Folk Medicine - A Review. Іnt. J. Mol. Sci. 2021. Vol. 22. No 19. P. 10746. DOI: https://doi.org/10.3390/ijms221910746 URL: https://www.mdpi.com/1422-0067/22/19/10746 DOI: https://doi.org/10.3390/ijms221910746
Shapovalova V. Forensic and Pharmaceutical Risks in the Organization of Pharmacotherapy of Covid, Post-Covid and Long-Covid Disorders. COVID-19 and Vaccination Practice Standards. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 4. Р. 1-24. DOI: https://doi.org/10.53933/sspmpm.v2i4.69 DOI: https://doi.org/10.53933/sspmpm.v2i4.69
Shapovalova V., Osyntseva А., Malekh Н. et al. Pharmacy of the future: Development of the thematic improvement cycle "Latest discoveries and prospects in the field of pharmacy". Actual Problems of Medicine and Pharmacy. 2024. Vol. 5. No 2. Р. 1-18. https://doi.org/10.52914/apmp.v5i2.66 DOI: https://doi.org/10.52914/apmp.v5i2.66
Shapovalova V. System of drugs circulation based on medical and pharmaceutical law. Actual Problems of Medicine and Pharmacy. 2021. Vol. 1. No. 1-2. Р. 1-14. URL: https://apmplmi.com/index.php/apmp/article/view/12 DOI: https://doi.org/10.52914/apmp-2021-1-6
The 2nd International scientific and practical conference “Perspectives of contemporary science: theory and practice” (April 1-3, 2024) SPC “Sciconf.com.ua”, Lviv, Ukraine. 2024. 1173 p. URL: https://sci-conf.com.ua/wp-content/uploads/2024/04/PERSPECTIVES-OF-CONTEMPORARY-SCIENCE-THEORY-AND-PRACTICE-1-3.04.2024.pdf
Grytsyk A., Struk, O., Stasiv T. Investigation of acute toxicity and hepaprotective effect of extracts of Nepeta cataria L. Actual Problems of Medicine and Pharmacy. 2021. Vol. 1. No 1-2. Р. 1-11. URL: https://apmplmi.com/index.php/apmp/article/view/22
Haiduchok I., Shapovalov V. Organizational and legal measures of state control of reforming and modernizing the health care on principles of pharmaceutical and medical law. Actual Problems of Medicine and Pharmacy. 2021. Vol. 1. No 1-2. Р. 1-8. URL: https://apmplmi.com/index.php/apmp/article/view/11
Shapovalova V., Shapovalov V., Negretsky S. Forensic and pharmaceutical problems concerning circulation of cannabis: perspectives of state control, medical and narcological health effects. Actual Problems of Medicine and Pharmacy. 2021. Vol. 1. No 1-2. Р. 1-4. URL: https://apmplmi.com/index.php/apmp/article/view/17
Voloshyn-Haponov I., Chernenko I., Voloshyna N. Structural and functional changes in organs of the abdominal cavity in patients with Wilson’s disease. International neurological journal. 2024. Vol. 20. No. 4. Р. 185-190. DOI: https://doi.org/10.22141/2224-0713.20.4.2024.1080 URL: https://scholar.google.com.ua/citations?hl=en&user=zagt0OIAAAAJ&view_op=list_works&sortby=pubdate DOI: https://doi.org/10.22141/2224-0713.20.4.2024.1080
Shapovalov V., Osyntseva A., Veits O. et al. Multidisciplinary Study of Alcohol Abuse from the Perspective of Pharmaceutical Law and Forensic Pharmacy. SSP Modern Law and Practice. 2024. Vol. 4. No 1. Р. 1-16. DOI: https://doi.org/10.53933/sspmlp.v4i1.133 DOI: https://doi.org/10.53933/sspmlp.v4i1.133
Shapovalov V., Veits O., Panchenko O. et al. Pharmacy and Dentistry: A Multidisciplinary Study of the Risks of Circulation of Medicinal Products. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No. 1. Р. 1-11. DOI: https://doi.org/10.53933/sspmpm.v4i1.132 DOI: https://doi.org/10.53933/sspmpm.v4i1.132
Shapovalov V., Veits O. Forensic and Pharmaceutical, Criminal and Legal, Social and Economic Study of the Conditions, that Cause Bribery Corruption in the System of Legal Relations "Doctor-Patient-Investigator-Lawyer". SSP Modern Law and Practice. 2022. Vol. 2. No 3. Р. 1-16. DOI: https://doi.org/10.53933/sspmlp.v2i3.57 DOI: https://doi.org/10.53933/sspmlp.v2i3.57
Kuzmishyna I. Medicinal Plants and Medicinal Raw Materials: Theory and Practice: Teaching and Methodological Manual. Lutsk: VezhaDruk. 2024. 248 p. URL: https://evnuir.vnu.edu.ua/bitstream/123456789/23772/1/Medicinal_Plants.pdf
Komar L.O., Shapovalova V.O., Shapovalov V.V. Certain Aspects of the Circulation of Combined Medicinal Products from the Position of Forensic Pharmacy. Scientific and Practical Conference with the Participation of International Specialists on Current Issues in the Fight against Infectious Diseases "Dedicated to the 170th Anniversary of the Birth of I.I. Mechnikov". Abstracts of Reports (May 14-15, 2015) / Responsible for the Publication Martynov A.V. Kharkiv: State Institution "Institute of Microbiology and Immunology named after I. I. Mechnikov NAMS of Ukraine", LLC "Center of Microbiology and Immunology" 2015. P. 25. URL: https://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
Kotov A.G., Kotova E.E., Sokolova O.O. Atlas of illustrations for methods of identification of medicinal plant raw materials in national monographs of the State Federal University. Kharkiv: State Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines". 2021. 256 p. URL: https://sphu.org/wp-content/uploads/2021/10/lrs_atlas_s.1-8.pdf
Shapovalova V.O., Shapovalov V.V., Sosin I.K. et al. Composition and control regime of extemporaneous sedative medicinal product: information sheet on innovations. Developed by: KhMAPO of the Ministry of Health of Ukraine, Ukrmedpatentinform of the Ministry of Health of Ukraine. K.: Ukrmedpatentinform of the Ministry of Health of Ukraine. 2016. No. 220–2016. Issue 14. 6 p.
Rogozhnikova O.V., Shapovalov V.V. Preferential provision of antiretroviral therapy in Ukraine based on pharmaceutical law. Scientific and practical conference with the participation of international specialists on current issues of combating infectious diseases "Dedicated to the 170th anniversary of the birth of I.I. Mechnikov". Abstracts of reports (May 14-15, 2015). State Educational Institution "Institute of Microbiology and Immunology named after I.I. Mechnikov NAMS of Ukraine”, LLC “Center for Microbiology and Immunology” 2015. P. 26. URL: https://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
Osyntseva A.O., Shapovalova V.O., Shapovalov V.V. Study of the combination of tuberculosis and alcoholism from the position of forensic pharmacy. Scientific and practical conference with the participation of international specialists on topical issues of the fight against infectious diseases "Dedicated to the 170th anniversary of the birth of I.I. Mechnikov". Abstracts of reports (May 14-15, 2015). State Institution "Institute of Microbiology and Immunology named after I.I. Mechnikov NAMS of Ukraine", LLC "Center of Microbiology and Immunology" 2015. P. 28. URL: https://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
Vasina Yu.V., Shapovalov V.V., Shapovalova V.A. Organization of provision of extemporaneous formulation of military hospitals in extreme situations based on pharmaceutical law. Scientific and practical conference with the participation of international specialists on topical issues of combating infectious diseases "Dedicated to the 170th anniversary of the birth of I.I. Mechnikov". Abstracts of reports (May 14-15, 2015). State Institution "Institute of Microbiology and Immunology named after I.I. Mechnikov NAMS of Ukraine", LLC "Center of Microbiology and Immunology" 2015. P. 29. URL: https://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
Shapovalov V.V. (II), Kapelnikova E.V., Shapovalova V.A., Shapovalov V.V. Study of the causes of medical errors from the point of view of medical and pharmaceutical law. Scientific and practical conference with the participation of international specialists on topical issues of combating infectious diseases "Dedicated to the 170th anniversary of the birth of I.I. Mechnikov". Abstracts of reports (May 14-15, 2015). State Institution "Institute of Microbiology and Immunology named after I.I. Mechnikov of the National Academy of Medical Sciences of Ukraine", LLC "Center of Microbiology and Immunology" 2015. P. 30. URL: https://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
Shapovalov V., Veits O. Medical and Pharmaceutical Law in Erasmus+: Study of the Disciplines by Medical Students as a Basis for Training of Healthcare Professionals in Prevention of Medical Errors and Crimes. SSP Modern Law and Practice. 2024. Vol. 4. No. 4. Р. 1-17. DOI: https://doi.org/10.53933/sspmlp.v4i4.169 DOI: https://doi.org/10.53933/sspmlp.v4i4.169
Shapovalov V., Veits O. Methadone Addiction: An Interdisciplinary Study of Trafficking, Abuse, and Disease. SSP Modern Law and Practice. 2024. Vol. 4. No. 3. Р. 1-24. DOI: https://doi.org/10.53933/sspmlp.v4i3.158 DOI: https://doi.org/10.53933/sspmlp.v3i3.108
Tsysnetska A., Chernikhovskyi M., Vujtsyk Y. Analysis of Dermatovenerological Pathology Among Military Personnel During Outpatient Clinic Admission in Ukraine. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No 4. Р. 1-13. DOI: https://doi.org/10.53933/sspmpm.v4i4.165 DOI: https://doi.org/10.53933/sspmpm.v4i4.165
Nevzghoda O. Modern Classification of Respiratory Diseases: Innovations in the International Classification of Diseases of the 11th Revision. SSP Modern Pharmacy and Medicine 2024. Vol. 4. No. 4. Р. 1-10. DOI: https://doi.org/10.53933/sspmpm.v4i4.162 DOI: https://doi.org/10.53933/sspmpm.v4i4.162
Nevzghoda O., Shapovalov V., Osyntseva A. et al. Codeines medicine: ABC/VED analysis, effectiveness and rationality of application. Annals of Mechnikov Institute. 2024. No. 4. P. 29-34. DOI: https://doi.org/10.5281/zenodo.14275098
Shapovalova V. Pharmacotherapy of Depressive Disorders in Conditions of Coronavirus Disease: Pharmacoeconomic Experimental Study. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No 3. Р. 1-11. DOI: https://doi.org/10.53933/sspmpm.v3i3.101 DOI: https://doi.org/10.53933/sspmpm.v3i3.101
Shapovalova V., Osyntseva A., Shapovalov V. et al. Pharmacognostic, Forensic and Pharmaceutical, Organizational and Legal, Clinical and Pharmacological Multidisciplinary Study with an Assessment of Peculiarities of Circulation (Use) of Smoking Mixtures of Spices and Entheogens of Amanita Muscaria Mushroom. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No. 3. Р. 1-13. DOI: https://doi.org/10.53933/sspmpm.v3i3.105 DOI: https://doi.org/10.53933/sspmpm.v3i3.105
Ryabukha O. Multidisciplinary Studies of the Thyroid Gland’s Synthetic Activity under Conditions of Iodine Deficiency Using Correlation Analysis. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No. 3. Р. 1-15. DOI: https://doi.org/10.53933/sspmpm.v3i3.104 DOI: https://doi.org/10.53933/sspmpm.v3i3.104
Ryabukha O. Mathematical methods in biomedical studies: The need for new approaches to study of follicular thyrocytes. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 2. P. 1–17. DOI: https://doi.org/10.53933/sspmpm.v2i2.47 DOI: https://doi.org/10.53933/sspmpm.v2i2.47
Ryabukha O. COVID-19 Pandemic encourages to deepen the study of the thyroid gland: Correlation portraits as a means of research in different directions of follicular thyrocytes activities. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 1. P. 1-21. DOI: https://doi.org/10.53933/sspmpm.v2i1.40 DOI: https://doi.org/10.53933/sspmpm.v2i1.40
Shapovalova V. Musculoskeletal health systematic review: clinical and pharmacological, organizational and legal, administration and pharmaceutical management aspects. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No. 2. P. 1-12. DOI: https://doi.org/10.53933/sspmpm.v4i2.134 DOI: https://doi.org/10.53933/sspmpm.v4i2.134
Shapovalova V. Multidisciplinary case studies of neuro-oncology disorders: administration, clinical and pharmacological, organizational and legal, pharmaceutical management. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No. 3. P. 1-11. DOI: https://doi.org/10.53933/sspmpm.v4i3.151 DOI: https://doi.org/10.53933/sspmpm.v4i3.151
Vasylovskyy V., Nehreba,T., Chernenko M. et al. Modern Experience of Pharmacotherapeutic Use and Effectiveness of Endolumbal Administration of Glucocorticoids in Progressive Types of Course for Multiple Sclerosis. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No. 3. Р. 1-10. DOI: https://doi.org/10.53933/sspmpm.v4i3.157. DOI: https://doi.org/10.53933/sspmpm.v4i3.157
Pyndus V., Shapovalov V. Study of Pharmaceutical Provision Under the Program of Medical Guarantees in Ukraine. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No. 3. Р. 1-10. DOI: https://doi.org/10.53933/sspmpm.v4i3.155 DOI: https://doi.org/10.53933/sspmpm.v4i3.155
Shapovalov V. Multidisciplinary Study of Medical Errors in the System of Legal Relations Between "Doctor-Patient-Pharmacist-Advocate" During the Circulation of Drugs. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No. 2. Р. 1-10. DOI: https://doi.org/10.53933/sspmpm.v3i2.88 DOI: https://doi.org/10.53933/sspmpm.v3i2.88
Shapovalova V. Extemporaneous Preparations in the Pharmacotherapy of Nervous System Disorders: Pharmaceutical Management, Marketing, Analysis, Application. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No 4. Р. 1-7. DOI: https://doi.org/10.53933/sspmpm.v3i4.111 DOI: https://doi.org/10.53933/sspmpm.v3i4.111
Pyndus T., Pyndus V., Dorosh I. et al. Dynamics of Changes in Bone Densitometric Parameters and the pH Level of Oral Fluid Among Children with Juvenile Idiopathic Arthritis During the Use of Developed Treatment and Prevention Complex. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No. 2. Р. 1-6. DOI: https://doi.org/10.53933/sspmpm.v3i2.91 DOI: https://doi.org/10.53933/sspmpm.v3i2.91
Shapovalova V., Shapovalov V., Shapovalov V. et al. The COVID-19 Pandemic (Strains "Delta", "Omicron"): Particularities of Study on the Thematic Cycle "General Pharmacy Based on Pharmaceutical Law". Actual Problems of Medicine and Pharmacy. 2022. 3. 1. 1-18. DOI: https://doi.org/10.52914/apmp.v3i1.36 DOI: https://doi.org/10.52914/apmp.v3i1.36
Shapovalova V.O., Vasina Y.V., Shapovalov V.V. et al. Study of turnover extemporaneous preparations in Ukraine on the basis of pharmaceutical law. Farmatsevtychnyi Zhurnal. 2016. No. 1. Р. 77-85. URL: https://pharmj.org.ua/index.php/journal/article/view/155
Shapovalova V.A., Shapovalov V.V. The clinical efficacy of the combined drug agent Valcophen in children. Likars'ka sprava. 1999. No. 1. P. 124-126. URL: https://pubmed.ncbi.nlm.nih.gov/10424023/
Shapovalova V.O., Mykhailov V.S., Shapovalov V.V. The characteristics of the development of cataleptic phenomena during the action of a new Ukrainian neuroleptic--a butyrophenone derivative – in experiments on mice. Fiziolohichnyi zhurnal. 1999. Vol. 45. No. 3. P.114-117. URL: https://pubmed.ncbi.nlm.nih.gov/10439301/
Shapovalov V.V., Rogozhnikova O.V. State principles of the medicines circulation regulation around the world and in Ukraine in the pharmacotherapy of orphan diseases among disabled children based on pharmaceutical law. Farmatsevtychnyi Zhurnal. 2015. No. 4. Р. 83-91. URL: https://pharmj.org.ua/index.php/journal/article/view/207
Shapovalov V.V., Zbrozhek S., Shapovalova V. et al. Organizational and legal regulation procedure for circulation of extemporal medicines based on pharmaceutical law. Annals of Mechnikov’s Institute. 2019. No. 4. Р. 33-37. URL: https://journals.uran.ua/ami/article/view/188930
Shapovalova V., Zbrozhek S., Shapovalov V., Shapovalov V. Content analysis of pharmacies in Ukraine where extemporaneous medicines are manufactured. Health of Society. 2022. Vol. 6. No. 3. Р. 77-83. DOI: https://doi.org/10.22141/2306-2436.6.3.2017.123498 DOI: https://doi.org/10.22141/2306-2436.6.3.2017.123498
Shapovalov V., Shapovalov V. Management of Prescription Medicines in Ukraine: Continuation of the Experimental Study on the Organization of Pharmaceutical Provision. SSP Modern Pharmacy and Medicine. 2024. Vol. 4. No. 2. Р. 1-11. DOI: https://doi.org/10.53933/sspmpm.v4i2.143 DOI: https://doi.org/10.53933/sspmpm.v4i2.143
Shapovalova V. Monkeypox Virus – New Challenges of Modernity: Experimental Organizational and Legal, Clinical and Pharmacological Studies. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 3. Р. 1-15. DOI: https://doi.org/10.53933/sspmpm.v2i3.54 DOI: https://doi.org/10.53933/sspmpm.v2i3.54
Shapovalov V., Zakalyk H., Gubaryeva O. Interdisciplinary Study on the Peculiarities of Preserving the Mental Health of Minors and Youth in Conditions of Martial Law. SSP Modern Law and Practice. 2025. Vol. 5. No.1. Р. 1-24. DOI: https://doi.org/10.53933/sspmlp.v5i1.171 DOI: https://doi.org/10.53933/sspmlp.v5i1.171
Shapovalova V.A., Sosin I.K., Butenko G.M. et al. Pharmaceutical law in narcology. Kharkov: “Fact”. 2004. 800 p.
Shapovalova V.O. The effect of Val'kofen tablets for children on the function of the gastrointestinal tract and liver in an experiment. Fiziol. Zh. 1995. Vol. 41. No. 5-6. Р. 111-116. URL: https://europepmc.org/article/med/9026383
Ivanishyn-Hayduchok L., Shapovalova V., Shapovalov V. ICD-11: organizational and legal, medical and pharmaceutical, social and economic issues of implementation of the program of state guarantees of medical care in 2022 in Ukraine, based on the fundamental principles of the European Union. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 2. P. 1-14. DOI: https://doi.org/10.53933/sspmpm.v2i2.53 DOI: https://doi.org/10.53933/sspmpm.v2i2.53
Chuiev Y., Shapovalova V. Integrated ABC/VEN-analysis of drug prescriptions in pharmacotherapeutic schemes for relief of drunken forms of alcohol dependence. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. Nо. 1. P. 1-14. DOI: https://doi.org/10.53933/sspmpm.v2i1.35 DOI: https://doi.org/10.53933/sspmpm.v2i1.35
Chuiev Y., Shapovalova, V. Interdisciplinary Pharmacoeconomic Study of Pharmacotherapy of Cupping of Drunk Forms of Alcohol Dependence: Clinical and Pharmacological, Organizational, Legal and Marketing Experiment. SSP Modern Pharmacy and Medicine. 2021. 1. 2. Р. 1-12. DOI: https://doi.org/10.53933/sspmpm.v1i2.24 DOI: https://doi.org/10.53933/sspmpm.v1i2.24
Gudzenko A.A., Shapovalov V.V. (Jr.), Shapovalova V.А. et al. Organizational and legal, forensic and pharmaceutical researches of pharmaceutical provision for mental disorders of victims in the emergencies at regional level. Likars’ka Sprava. 2018. Vol. 7-8. P. 149-157. DOI: https://doi.org/10.31640/JVD.7-8.2018(24) DOI: https://doi.org/10.31640/JVD.7-8.2018(24)
Shapovalov V., Linsky I. Forensic and pharmaceutical study of the pharmacotherapy of opioid withdrawal syndrome among patients-offenders with different levels of opium addiction on a base of evidence-based pharmacy. Farmatsevtychnyi Zhurnal. 2012. No. 1. Р. 20-27. URL: https://pharmj.org.ua/index.php/journal/article/view/546
Shapovalov V., Linskiy I. Forensic pharmacy, forensic narcology: scoring method of the predisposing to psychical and behavioral frustrations health by reason of psychoactive substances abusing. Farmatsevtychnyi Zhurnal. 2010. No. 1. Р. 36-41. URL: https://pharmj.org.ua/index.php/journal/article/view/864 DOI: https://doi.org/10.53841/bpsfu.2010.1.100.36
Shapovalov V., Linsky I. Forensic pharmacy: the study of disposition to health addictive disorders pf the drug addiction patients with deviant behavior. Farmatsevtychnyi Zhurnal. 2011. No. 6. Р. 30-34. URL: https://pharmj.org.ua/index.php/journal/article/view/564
Shapovalov V.V., Linskiy I.V. Evidence-based pharmacy: definition of the control regime for the medicines in the pharmaceutical correction schemes of the opioid dependence. Farmatsevtychnyi Zhurnal. 2013. No. 3. Р. 35-40. URL: https://pharmj.org.ua/index.php/journal/article/view/399
Shapovalov V., Linsky I. Influence of the genetic and environmental components on the addictive dependence development of the drug addicted patients with deviant behavior (forensic and pharmaceutical aspects). Farmatsevtychnyi Zhurnal. 2011. No. 5. Р. 30-34. URL: https://pharmj.org.ua/index.php/journal/article/view/585
Petrenko V., Shapovalova V., Koneva V. et al. Forensic and pharmaceutical monitoring of the spread of health problems between women with drug addiction. Farmatsevtychnyi Zhurnal. 2011. No. 4. Р. 35-38. URL: https://pharmj.org.ua/index.php/journal/article/view/629
Radionova V.A., Shapovalova V.A., Linsky I.V. et al. Forensic pharmacy and narcology: psychological features as indicators ofsusceptibility to the development of addictive disorders health in women. Farmatsevtychnyi Zhurnal. 2013. No. 1. Р. 32-37. URL: https://pharmj.org.ua/index.php/journal/article/view/430
Shapovalov V., Vasina Y., Shapovalova V. et al. Forensic pharmaceutical research problems hearing disorders in patients suffering from addictive disorders due to health substance abuse. Farmatsevtychnyi Zhurnal. 2012. No. 4. Р. 33-36. URL: https://pharmj.org.ua/index.php/journal/article/view/493
Shapovalovа V., Mysoev S., & Shapovalov V. Forensic pharmacy: the formation of the international traffic control narcotic drugs in countering the drug threat. Farmatsevtychnyi Zhurnal. 2012. No. 1. Р. 28-33. URL: https://pharmj.org.ua/index.php/journal/article/view/547
Shapovalov V. Study of the control mode of drugs for pharmaceutical correction of the patients’ opioid dependence on a base of forensic pharmacy. Farmatsevtychnyi Zhurnal. 2011. No. 4. Р. 31-34. URL: https://pharmj.org.ua/index.php/journal/article/view/628
Matsko N. Rehabilitation of patients who have suffered facial neuritis. Actual Problems of Medicine and Pharmacy. 2024. Vol. 5. No. 2. Р. 1-16. DOI: https://doi.org/10.52914/apmp.v5i2.68 DOI: https://doi.org/10.52914/apmp.v5i2.68
Arora D., Rani A., and Sharma A.A Review on Phytochemistry and Ethnopharmacological Aspects of Genus Calendula. Pharmacognosy Review. 2013. Vol. 7. No. 14. P. 179-187. URL: https://www.phcogrev.com/article/2013/7/14/1041030973-7847120520 DOI: https://doi.org/10.4103/0973-7847.120520
Sharma S., Kumari K. An overview on calendula officinalis linn.: (POT MARIGOLD). Journal of Advanced Scientific Research. 2021. Vol. 12. No.03. Suppl 2. Р. 13-18. https://doi.org/10.55218/JASR.s2202112302 DOI: https://doi.org/10.55218/JASR.s2202112302
Calendulae Flores. Liktravy. 28.12.2023. URL: https://liktravy.ua/herbs/kalenduly-kvitky
Kandybey N. What does calendula treat? Useful properties and contraindications. Pharmaceutical factory "Viola". 11.10.2024. URL: https://violapharm.com/en/what-does-calendula-treat-useful-properties-and-contraindications/
Givol O., Kornhaber R.A., Visentin D. et al. A systematic review of Calendula officinalis extract for wound healing. Wound Repair and Regeneration. May 2019. Vol. 27. No. 5. P. 548-561. URL: https://doi.org/10.1111/wrr.12737 DOI: https://doi.org/10.1111/wrr.12737
Preparations and medicines containing Calendula 7 pcs. in the catalog. Apteka24.ua.
Gryzodoub O., Shapovalov V. Quality Systems in Pharmacy: Multidisciplinary Context of the State Pharmacopoeia of Ukraine. SSP Modern Law and Practice. 2023. Vol. 3. No. 1. Р. 1-23. DOI: https://doi.org/10.53933/sspmlp.v3i1.81 DOI: https://doi.org/10.53933/sspmlp.v3i1.81
British Herbal Pharmacopoeia. London: British Herbal Medicine Association, 1996. – 212.p
British Pharmacopoeia. London: HMSO, 2009. – Vol. 3. – 6813 – 6816 P.
Český Lékopis. http://www.lekopis.cz/
Calendula flower. European Pharmacopoeia, 11th ed. Strasbourg: European Department for the Quality of Medicines, 2020. р. 1438-1440.
Ringelblumen bluten. Deutsches Arzneibuch 10. Ausgabe 1991. 2. Grundifg, 1996. Frankfurt: Deutscher Apotheker Verlag, 1996.-Bd.4.
Calendula flos. State Pharmacopoeia of Ukraine. State Enterprise “Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines”. 2nd Edition. Vol. 3. Kharkiv: State Enterprise “Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines”, 2014. Vol. 3. 400-402 P.
Calendulae tincture. State Pharmacopoeia of Ukraine. State Enterprise «Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines». 2nd Edition. Vol. 3. Kharkiv: State Enterprise «Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines», 2014. Vol. 3. 402-403 P.
State Pharmacopoeia of Ukraine: in 3 vols. State Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines". 2nd ed. Kharkiv: State Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines", 2015. Vol. 1. 609 p.
State Pharmacopoeia of Ukraine: in 3 vols. State Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines". 2nd ed. Kharkiv: State Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines", 2015. Vol. 1. 697 p.
State Pharmacopoeia of Ukraine: in 3 vols.vState Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines". 2nd ed. Kharkiv: State Enterprise "Ukrainian Scientific Pharmacopoeial Center for the Quality of Medicines", 2015. Vol. 1. 736 p.
Kotova E.E. Standardization of preparations of plant and animal origin containing flavonoids and fatty oils: Diss. Candidate of Pharmaceutical Sciences. Kharkiv, 2005. 158 p.
Fructus Hіppophaеs Bogatyr.club. 2025. URL: https://bogatyr.club/51758-jagody-oblepihi.html
Hippophae nrhamnoides L. Virdol. 2025. URL: https://virdol.com.ua/roslini/oblipyha-krushinovidna
Useful properties of mountain ash and chokeberry. Ukrinform. 15.01.2021. URL: https://www.ukrinform.ua/rubric-other_news/3170272-korisni-vlastivosti-gorobini-zvicajnoi-ta-cornoplidnoi-infografika.html
Common edible mountain ash / Sorbus aucuparia var. Edulis. Zelena Bukhta. 2025. URL: https://zelenabuhta.com.ua/product/gorobyna-zvychajna-yistivna-sorbus-aucuparia-var-edulis/
Description and characteristics of the black currant plant. Agrarii razom. 2025. URL: https://agrarii-razom.com.ua/plants/chorna-smorodina
Currant - the benefits of black berries and contraindications. UNIAN. 17.06.2020. URL: https://www.unian.ua/health/country/smorodina-korist-chornoji-smorodini-novini-ukrajini-11039270.html
Dog rose (dog rose). Institute of Evolutionary Ecology of the National Academy of Sciences of Ukraine. 2025. URL: https://www.ieenas.org/p/shipshina-zvichaina-roza-sobacha/
Dog rose Rosae fructus. Liktravy. 12/28/2023. URL: https://liktravy.ua/herbs/shypshyny-plody
Skavron B. For what diseases will Ukrainians be prescribed medical cannabis. Ministry of Health. TSN. 27.09.2024. URL: https://tsn.ua/zdorovya/za-yakih-hvorob-ukrayincyam-priznachatimut-medichniy-kanabis-moz-2668695.html
Cannabis flowers. https://www.dls.gov.ua/news/
Cannabis flower. State Pharmacopoeia of Ukraine. State Enterprise «Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines». 2nd Edition. Supplement 7. Kharkiv: State Enterprise «Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines», 2024. Vol. 2. 350-354 p.
Pashynska K. Cannabis-based medicines have been registered in Ukraine. Ukrainian Medical Journal. 14.01.2025. URL: https://umj.com.ua/uk/novyna-262085-v-ukrayini-projshli-reyestratsiyu-liki-na-osnovi-kanabisu
Shafeie N., Naini A.T, Jahromi H.K. Comparison of Different Concentrations of Calendula Officinalis Gel on Cutaneous Wound Healing. Biomed. Pharmacol. J. 2015. Vol. 8. No. 2. H. URL: https://biomedpharmajournal.org/vol8no2/comparison-of-different-concentrations-of-calendula-officinalis-gel-on-cutaneous-wound-healing/ DOI: https://doi.org/10.13005/bpj/850
Yakovlev A.I., Konoplia A.I., Yakovlev F. AND. Research of polysaccharides of the medicinal raw material Salendula-officinalis. Bull. "New technology". 1999.No. 3. P. 60-61.
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