Interdisciplinary Study of Health Disorders Associated with Comorbid Addictions

Authors

DOI:

https://doi.org/10.53933/sspmpm.v3i3.109

Keywords:

health disorders, major somatic diseases, lung pathologies, accompanying comorbid addictive conditions, psychoactive substances, abuse

Abstract

This study presents an interdisciplinary examination of health disorders associated with comorbid addictions. Drawing on data from medical, psychological, and sociological sources, we analyzed the interrelated impacts of multiple concurrent addictions on individuals' physical, psychological, and social health. Our findings indicate that individuals with comorbid addictions face compounded health risks and often experience exacerbated symptoms compared to those with singular addictions. Additionally, the societal perception and treatment of these individuals are often influenced by stigma, leading to decreased access to comprehensive healthcare and support. Proven that there are cause-and-effect relationships between the consumption of prohibited psychoactive substances, the formation of concomitant comorbid addictive conditions, and drug-related crime. It is noted that the comorbid addictive state depends on the classification and legal group of the psychoactive substance or drug. Common, simultaneous use of psychoactive narcotic analgesics, psychoactive psychotropic tranquilizers, cannabis, amphetamine, alcohol, other psychoactive substances, and drugs. Measures are proposed for further study of the problem to improve the quality of medical and pharmaceutical care, pharmaceutical provision, protection of the rights of patients of various contingents to medical and pharmaceutical rights.

Author Biography

Olexandr Nevzghoda, Danylo Halytsky Lviv National Medical University

PhD in Medical Sciences, Associate Professor

Danylo Halytsky Lviv National Medical University, Ukraine

Lviv Medical University, Ukraine

E-mail: sashko.nev0703@gmail.com

 

References

Sosin I.K., Chuev Yu.F., Shapovalov V.V., Shapovalova V. et al. Narcology: national textbook. Kharkiv, Ukraine: Kolegium. 2014. 948 p.

Shapovalov V.V., Linsky I.V. Forensic pharmacy: the study of disposition to health addictive disorders pf the drug addiction patients with deviant behavior. Pharmaceutical journal. 2011. Issue 6. P. 30-34. URL: https://pharmj.org.ua/index.php/journal/article/view/564.

Shapovalov V.V., Linsky I.V. Forensic pharmacy, forensic narcology: scoring method of the predisposing to psychical and behavioral frustrations health by reason of psychoactive substances abusing. Pharmaceutical journal. 2010. Issue 1. P. 36-41. URL: https://pharmj.org.ua/index.php/journal/article/view/864.

Shapovalova V. Forensic and pharmaceutical risks in the organization of pharmacotherapy of covid, post-covid and long-covid disorders. COVID-19 and vaccination practice standards. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No. 4. P.1–24. URL: https://doi.org/10.53933/sspmpm.v2i4.69.

Nehretskii S. Forensic and pharmaceutical, organizational and legal studies of illegal circulation, danger and drug addiction from cannabinoids. SSP Modern Pharmacy and Medicine. 2022. Vol.2. No.4. P.1-15. URL: https://doi.org/10.53933/sspmpm.v2i4.71.

Shapovalov V. Forensic pharmacy, organization of pharmaceutical business, drug technology, medical, pharmaceutical and criminal law: the state system of combating the illegal circulation of narcotic drugs and psychotropic substances and their abuse in pandemic condition. SSP Modern Law and Practice. 2022. Vol.2. No.3. P.1-35. URL: https://doi.org/10.53933/sspmlp.v2i3.66.

Shapovalov V.V., Gudzenko A.A., Shapovalova V.O. et al. Forensic and pharmaceutical analysis of addictive morbidity because of the use of psychotropic psychoactive substances in Ukraine (retrospective aspect). Annals of Mechnikov Institute. 2018. N. 3. Р. 41–44. DOI: 10.5281/zenodo.1456544. URL: http://www.imiamn.org.ua/journal/3_2018/PDF/9.pdf.

Shapovalova V.A., Zbrozhek S.I., Shapovalov V.V. et al. Forensic pharmacy: some risk factors in the formation of addictive health disorders. Acta Scientific Pharmaceutical Science. 2021. Vol.5. Iss.1. P.54-59. DOI: 10.31080/ASPS.2020.05.0651. URL: https://actascientific.com/ASPS/ASPS-05-0651.php.

Shapovalov V., Diachenko A. Interdisciplinary Forensic and Pharmaceutical Study of Illegal circulation of falsified alcoholic beverages to combat crime and prevent Public Health disorders. SSP Modern Pharmacy and Medicine. 2023. Vol.3. No.1. P.1-12. URL: https://doi.org/10.53933/sspmpm.v3i1.86.

Shapovalov (Jr.) V., Zbrozhek S., Gudzenko A. еt al. Organizational and legal analysis of the pharmaceutical provision for the most common diseases of society. International Journal of Pharmaceutical Sciences Review and Research. 2018. Vol.51. N.1. P. 118-124. URL: http://globalresearchonline.net/journalcontents/v51-1/18.pdf.

Shapovalova V. Monkeypox virus – new challenges of modernity: experimental organizational and legal, clinical and pharmacological studies. SSP Modern Pharmacy and Medicine. 2022. Vol.2. N.3. P.1–15. URL: https://doi.org/10.53933/sspmpm.v2i3.54.

Shapovalova V. An Innovative multidisciplinary study of the availability of coronavirus vaccines in the world. SSP Modern Pharmacy and Medicine. 2022. Vol.2. N.2. P.1–17 URL: https://doi.org/10.53933/sspmpm.v2i2.45.

Hayduchok I., Shapovalova V., Ishcheikin K. et al. Pharmaeconomic approaches for pharmacotherapy of Rheumatoid arthritis. Likars’ka Sprava. 2021. No. 1–2. P.70-79. URL: https://liksprava.com/index.php/journal/article/view/463. DOI: https://doi.org/10.31640/JVD.1-2.2021(11).

4. Hayduchok I. Pharmacotherapy of psoriasis support with antiphospholipid syndrome: ABC/VEN analysis of anti-viral drugs. SSP Modern Pharmacy and Medicine. 2021. Vol.1. No.1. P.1-12. URL: https://doi.org/10.53933/sspmpm.v1i1.4.

Pyndus T., Pyndus V., Dorosh, I. et al. Dynamics of changes in bone densitometric parameters and the pH level of oral fluid among children with juvenile idiopathic arthritis during the use of developed treatment and prevention complex. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No 2. Р. 1-6. URL: https://doi.org/10.53933/sspmpm.v3i2.91.

Nevzhoda A., Nevzhoda O. Immunological criteria of autoaggression of bronchial asthma: markers for prediction of the course and selection of adequate pharmacotherapy. SSP Modern Pharmacy and Medicine. 2023. Vol. 3. No 1. P. 1-7. URL: https://doi.org/10.53933/sspmpm.v3i1.84/.

Tsysnetska А. To the question of modern diagnosis and deferential diagnosis of severe dermatoses: toxic epidermal necrolysis and steven-johnson syndrome. Actual Problems of Medicine and Pharmacy. 2022. Vol. 3. No 2. Р. 1-11. URL: https://doi.org/10.52914/apmp.v3i2.47.

Shapovalova V. Interdisciplinary pharmacoeconomic research concerning the pharmacotherapy of Аlcoholic Hepatitis in conditions of COVID-19 pandemic. SSP Modern Pharmacy and Medicine. 2023. Vol.3. No.2. P.1-10. URL: https://doi.org/10.53933/sspmpm.v3i2.87

Shapovalova V. Pharmacotherapy of Depressive disorders in conditions of coronavirus disease: pharmacoeconomic experimental study. SSP Modern Pharmacy and Medicine. 2023. Vol.3. No.3. P.1-11. URL: https://doi.org/10.53933/sspmpm.v3i3.101.

Shapovalov V. Suicide among young people in Ukraine and Estonia: interdisciplinary study of the problem in the system of legal relations "doctor-patient-pharmacist-lawyer". SSP Modern Pharmacy and Medicine. 2023. Vol.3. No.3. P.1-16. URL: https://doi.org/10.53933/sspmpm.v3i3.106.

Shapovalov V.V. (Jr.), Shapovalova V.A., Shapovalov V.V. Forensic and pharmaceutical research on the impact of drugs on the safety, life and health of road users within the organization of pharmaceutical business, drug technology, pharmaceutical and medical law in Ukraine. Health of Society. 2021. Vol.10. Nо.4. P.127-132. URL: https://doi.org/10.22141/2306-2436.10.4.2021.246355.

Shapovalov V. Interdisciplinary legal, forensic and pharmaceutical, forensic and chemical, forensic and narcological, forensic and toxicological, criminal and legal study of the illegal trafficking of Amphetamine. SSP Modern Law and Practice. 2023. Vol.3. No.3. P.1-14. URL: https://doi.org/10.53933/sspmlp.v3i3.108.

Criminal Code of Ukraine. Verkovna Rada of Ukraine. URL: https://zakon.rada.gov.ua/laws/show/2341-14/page15#Text.

Ivashchenko Yu.B. Drug addiction and its consequences. All-Ukrainian Narcological Center "Medicon". 12.06.2021. URL: https://nonarcotic.com.ua/uk/statti/250-toksykomaniia-i-ii-naslidky/.

Drug addiction as a type of drug addiction. Leader REHAB. 08.07.2019. URL: https://leader-klinika.com.ua/toksikomanija-kak-vid-narkomanii/#

UNODC World Drug Report 2023 warns of converging crises as illicit drug markets continue to expand. UN. 26.06.2023. URL: https://www.unodc.org/unodc/en/press/releases/2023/June/unodc-world-drug-report-2023-warns-of-converging-crises-as-illicit-drug-markets-continue-to-expand.html.

World Drug Report 2023. UN. 2023. URL: https://www.unodc.org/unodc/en/data-and-analysis/world-drug-report-2023.html.

European Drug Report 2023: Trends and Developments. EMCDDA. 2023. URL: https://www.emcdda.europa.eu/index_en.

Shankar Р. Drug sales and violence up in EU, report finds. DW. 16.06.2023. URL: https://www.dw.com/en/drug-sales-and-violence-up-in-eu-report-finds/a-65925529.

Constitution of Ukraine. Verkhovna Rada of Ukraine. 1996. No. 30. Art. 141. URL: https://zakon.rada.gov.ua/laws/show/254%D0%BA/96-%D0%B2%D1%80#Text.

Bakaliuk O., Oliynyk N. Youth and psychoactive substances: risk factors and protection. Psychology and society. 2011. No. 3 (45). P. 70-95.

Levchuk N.M. Socio-demographic consequences of drug addiction in the context of the HIV/AIDS epidemic in Ukraine. Demography and social economy. 2006. No. 1. P. 55-65.

Shapovalova V.A., Stefanov A.V., Trakhtenberg I.M. et al. Pharmaceutical law in safe self-treatment: drugs dispensed without a doctor's prescription. 2nd ed. Kh.: FAKT. 2005. 800 p.

Shapovalov V., Shapovalova V., Vasina Y. Proving pharmacy and forensic pharmacy: features of polinarcomania among young people. Farmatsevtychnyi Zhurnal. 2008. No.5. P.51-56. URL: https://pharmj.org.ua/index.php/journal/article/view/1096.

Shapovalov V.V., Linsky I.V. Forensic pharmacy: the study of disposition to health addictive disorders pf the drug addiction patients with deviant behavior. Pharmaceutical journal. 2011. Issue 6. P. 30-34. URL: https://pharmj.org.ua/index.php/journal/article/view/564.

Shapovalova V. Alcoholic Hepatitis: an experimental meta-analysis. SSP Modern Pharmacy and Medicine. 2023. Vol.3. No.1. P.1-11. DOI: https://doi.org/10.53933/sspmpm.v3i1.77.

Shapovalova V.A., Shapovalov V.V. The clinical efficacy of the combined drug agent Valcophen in children. Likars'ka sprava. 1999. No.1. P.124–126. URL: https://pubmed.ncbi.nlm.nih.gov/10424023/.

Shapovalova V.O., Mykhailov V.S., Shapovalov V.V. The characteristics of the development of cataleptic phenomena during the action of a new Ukrainian neuroleptic--a butyrophenone derivative--in experiments on mice. Fiziolohichnyi zhurnal. 1999. Vol.45. No.3. P 114–117. URL: https://pubmed.ncbi.nlm.nih.gov/10439301/.

“Moly”, a drug whose name sounds innocent, has disastrous and deadly side effects. Fund "For peace without drugs". 2023. URL: https://www.notodrugs.ru/newsletter/volume4/issue3/molly-a-drug-that-sounds-innocent-has-disastrous-and-deadly-side-effects.html.

Arkharova K. Legal drugs: they don't have time to stop them. BBC. 15.05.2011. URL: https://www.bbc.com/russian/uk/2011/05/110515_legal_highs.

Shapovalov V. Forensic pharmacy, organization of pharmaceutical business, drug technology, medical, pharmaceutical, and criminal law: the state system of combating the illegal circulation of narcotic drugs and psychotropic substances and their abuse in pandemic condition. SSP Modern Law and Practice. 2022. Vol.2. No.3. P.1-35. URL: https://doi.org/10.53933/sspmlp.v2i3.66.

Shapovalov V. Illegal drug laboratories: forensic and pharmaceutical, forensic and expert, forensic and toxicological, forensic and chemical, criminal and legal examination to combat drug trafficking, illegal circulation of prohibited psychoactive substances, morbidity. SSP Modern Law and Practice. 2023. Vol.3. No.2. P.1-19. URL: https://doi.org/10.53933/sspmlp.v3i2.100.

Kuzminov V.N., Lynsky I.V., Nazarchuk A.G. et al. Peculiarities of addiction to opiates during tramadol abuse. Ukrainian Herald of Psychoneurology. 2001. T. 9. Issue 4. P. 27-28. URL: http://www.psychiatry.ua/articles/paper015.htm.

Shapovalov V.V., Khalin M.M., Shapovalova V.O. et al. Drug addiction: problems, features, warnings. Ukrainian Herald of Psychoneurology. 2002. T. 10. Issue 1. P. 200-204. URL: http://www.psychiatry.ua/articles/paper069.htm.

Shapovalov V., Shapovalova V., Malinina N. The forensic-pharmaceutical characteristic of control-allowing system concerning a turn precursors. Farmatsevtychnyi Zhurnal. 2008. No.4. P.37-40. URL: https://pharmj.org.ua/index.php/journal/article/view/1116.

Law of Ukraine "On narcotic drugs, psychotropic substances and precursors". Verkhovna Rada of Ukraine. 1995. No. 10. Article 60. URL: https://zakon.rada.gov.ua/laws/show/60/95-%D0%B2%D1%80#Text.

Law of Ukraine "On measures to counter the illegal circulation of narcotic drugs, psychotropic substances and precursors and their abuse". Verkhovna Rada of Ukraine. 1995. No. 10. Article 62. Edition of 31.03.2023. URL: https://zakon.rada.gov.ua/laws/show/62/95-%D0%B2%D1%80#Text.

Osadchii A.I. COVID-19: dangerous complications. Ukrainian Medical Journal. 12.02.2021. URL: https://umj.com.ua/uk/publikatsia-198900-covid-19-nebezpechni-uskladnennya.

Esmaeel H.M., Radwan R.A. Outcome of primary spontaneous pneumothorax: Could drug abuse have an effect? Egyptian Journal of Chest Diseases and Tuberculosis. 2017. Vol. 66. Issue 3. P. 441-444. URL: https://staffsites.sohag-univ.edu.eg/stuff/posts/show/7432?p=posts.

Cohen H., Cohen S. Spontaneous bilateral pneumothorax in drug addicts. DOI: 10.1378/chest.86.4.645. URL: https://pubmed.ncbi.nlm.nih.gov/6478912/.

Shapovalov V.V., Shapovalova V.A., Melnichenko A.M. et al. Forensic pharmacy, pharmaceutical law and medical law as a tool of the Ministry of Health of Ukraine and the Ministry of Internal Affairs of Ukraine in studying the facts of murders and suicides due to the use of psychoactive substances or untimely medical and pharmaceutical care. Drugs of Ukraine. 2007. No. 112 (addendum). pp. 170-179. URL: http://www.psychiatry.ua/articles/paper318.htm.

Following the appeal of the Cherkasy prosecutor, the drug dealer again leaned under the bar. ViCherpno. 17.04.2023. URL: https://vycherpno.ck.ua/za-apelyacziyeyu-cherkaskogo-prokurora-narkotorgivecz-znovu-opynyvsya-pid-vartoyu/.

Swede O. They caught a Cherkasy woman, who sold drugs from Ugry region via Telegram. Suspіlne. 18.02.2023. URL: https://suspilne.media/389144-zatrimali-cerkasanku-aka-zi-spilnikom-prodavala-narkotiki-z-ugorsini-cerez-telegram/.

Crack of drugs – 4 bagmen from Lviv took a drink. Lviv Regional Prosecutor's Office. 14.07.2023. URL: https://lviv.gp.gov.ua/ua/news.html?_m=publications&_t=rec&id=338137&fp=30https://lviv.gp.gov.ua/ua/news.html?_m=publications&_t=rec&id=338137&fp=30.

Until the real release of the will, drug trafficking in the Cherkasy region was condemned. Cherkasy regional prosecutor's office. 07/04/2023. URL: https://chk.gp.gov.ua/ua/news.html?_m=publications&_t=rec&id=337461&fp=70.

Investigators of the Poltava region's police are installing a traffic accident, in which two people perished. National Police in Poltava region. 25.06.2023. URL: https://pl.npu.gov.ua/news/slidchi-politsii-poltavshchyny-vstanovliuiut-obstavyny-dtp-v-iakii-zahynulo-dvoie-liudei.

Denkovich Ya. In Kremenchug, a young man “drug-stricken” to death beating lads on a pishohidny passage. TSN. 25.06.2023. URL: https://tsn.ua/ukrayina/u-kremenchuci-molodik-pid-narkotikami-na-smert-zbiv-hlopciv-na-pishohidnomu-perehodi-2357161.html.

Klekit H. Synthetic drugs for the body – like a nuclear vibe. High castle. 11.10.2018. URL: https://wz.lviv.ua/interview/378767-syntetychni-narkotyky-dlia-orhanizmu-iak-iadernyi-vybukh.

Zozulya I.S., Volosovets A.O., Zozulya A.I. Anesthesiology and intensive therapy, emergency medicine. Ukrainian Medical Journal. VII/VIII 2021. No. 4 (144). P. 20-25. URL: https://umj.com.ua/uk/stattia-214030-travma-travmatichnij-shok-diagnostika-ta-nadannya-nevidkladnoyi-dopomogi.

El-Safty I., Eltamany E., Shouman A. et al. Effect of tramadol addiction alone and its co-abuse with cannabis on urinary excretion of Copper, Zinc, and Calcium among Egyptian addicts. Afr. Health Sci. 2018. Vol.18. No.3. Р.767-775. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307004/.

Shapovalov V., Linsky I. Forensic and pharmaceutical study of the pharmacotherapy of opioid withdrawal syndrome among patients-offenders with different levels of opium addiction on a base of evidence-based pharmacy. Farmatsevtychnyi Zhurnal. 2012. No.1. Р.20-27. URL: https://pharmj.org.ua/index.php/journal/article/view/546.

Shapovalov V.V. (Jr.), Shapovalova V.A., Shapovalov V.V. Development of forensic and pharmaceutical researches within the organization of pharmaceutical business, drug technology and pharmaceutical law in Ukraine concerning the turnover of controlled drugs and substances. Health of Society. 2021. Vol.10. Nо.3. P.98-106. URL: https://doi.org/10.22141/2306-2436.10.3.2021.246351.

Haiduchok I., Tukhar I., Shapovalov V. Chronic pancreatitis, comorbid with alcohol addiction: epidemiology, causes, developmental features, symptoms and supportive pharmaceutical therapy. SSP Modern Pharmacy and Medicine. 2022. Vol.2. N.2. P.1-13. URL: https://doi.org/10.53933/sspmpm.v2i2.46.

Amneh Al-Husseini, Wazaify M., Claire Van Hout. Pregabalin misuse and аbuse in Jordan: a qualitative study of user еxperiences. Int. J. Ment. Health. Addiction. 2018. No.16 Р. 642-654. URL: DOI: https://doi.org/10.1007/s11469-017-9813-4.

Brednev I.V. I need xanax – rest addiction. Medlux Medical Center. 2023. URL: https://medlux.net.ua/ru/narcologia/mne-nuzhen-ksanaks-zavisimost-ot-pokoya/.

Lil Peep death at age 21 likely due to overdose of xanax anti-anxiety medication, say Arizona police. Dailymail. 17.11.2017. URL: https://www.dailymail.co.uk/tvshowbiz/article-5091393/Lil-Peep-death-age-21-likely-overdose-Xanax.html.

Lockett J. Rap star's 'drug death' rapper Lil Peep died from ‘overdose of the prescription anxiety pill Xanax’ on tour bus, cops say Cops say the rising star's manager found him unresponsive and surrounded by drugs paraphernalia. The Sun UK Edition. 17.11.2017. URL: https://www.thesun.co.uk/news/4939826/rapper-lil-peep-died-from-overdose-of-the-prescription-pill-xanax-on-tour-bus-cops-say/.

Valentin А. Can you take xanax with tramadol? Clearbrookinc. 21.12.2021. URL: https://www.clearbrookinc.com/news/can-you-take-xanax-with-tramadol/.

Tramadol аddiction. Whichrehab. 2023. URL: https://whichrehab.co.uk/tramadol-addiction/.

Buprenorphine – danger of taking, treatment. Narcological center "Tonus Plus". 2023. URL: https://tonus.kiev.ua/buprenorfin-opasnost-priema/.

Antukh A.M. The drug Xanax is a deadly sedative. Rehabilitation Center "New Life". 2023. URL: https://nc-newlife.com/ua/statti/preparat-ksanaks-smertelne-zaspokijlive.

Preuss C.V., Kalava А., King К.С. Prescription of controlled substances: benefits and risks. NLM. 29.04.2023. URL: https://www.ncbi.nlm.nih.gov/books/NBK537318/.

Shapovalova V. The ICD-11 for the twenty-first century: the first view from the organizational, legal, clinical and pharmacological aspects. SSP Modern Pharmacy and Medicine. 2022. Vol.2. N.1. P.1-13. URL: https://doi.org/10.53933/sspmpm.v2i1.37.

Ivanishyn-Hayduchok L., Shapovalova V., Shapovalov V. ICD-11: Organizational and legal, medical and pharmaceutical, social and economic issues of implementation of the program of state guarantees of medical care in 2022 in Ukraine, based on the fundamental principles of the European Union. SSP Modern Pharmacy and Medicine. 2022. Vol.2. No.2. P.1-14. URL: https://doi.org/10.53933/sspmpm.v2i2.53.

Pylypiv O., Pylypiv L. The growing role of humanitarian knowledge in modern conditions: cultural values of antiquity as a tool of influence on the professional development of the competencies of future medical specialists and pharmacists. SSP Modern Pharmacy and Medicine. 2022. Vol. 2. No 3. Р. 1-11. URL: https://doi.org/10.53933/sspmpm.v2i3.68.

Shapovalov V., Shapovalov V., Peresypkin A. The features of turn-over drugs with codeine different nomenclature and low groups. Farmatsevtychnyi Zhurnal. 2010. No.4. Р.10-14. URL: URL:https://pharmj.org.ua/index.php/journal/article/view/771.

Shapovalova V., Ukhta L., Shapovalov V. Forensic and pharmaceutical analysis of holders of license for circulation of controlled medicinal products in Ukraine. Farmatsevtychnyi Zhurnal. 2008. No.6. Р.41-47. URL: https://pharmj.org.ua/index.php/journal/article/view/1073.

Downloads

Published

2023-08-18

How to Cite

Nevzghoda, O. (2023). Interdisciplinary Study of Health Disorders Associated with Comorbid Addictions. SSP Modern Pharmacy and Medicine, 3(3), 1–13. https://doi.org/10.53933/sspmpm.v3i3.109

Issue

Section

Health Sciences. Medicine