INTEGRATED ABC/VEN-ANALYSIS OF DRUG PRESCRIPTIONS IN PHARMACOTHERAPEUTIC SCHEMES FOR RELIEF OF DRUNKEN FORMS OF ALCOHOL DEPENDENCE

An integrated ABC/VEN analysis of drug prescriptions in pharmacotherapeutic schemes for the relief of alcoholic dependence was performed. A retrospective analysis of seventy-five anonymized case histories of patients who sought medical help with drunken forms of alcoholic dependence was processed. The scheme of basic pharmacotherapy of relief of drunken forms of alcoholic dependence, developed by associate professor Yurii Chuiev for carrying out interdisciplinary study was used. Substantiated that the introduction of the developed innovative treatment algorithm, with the use of laser therapy, infusion therapy, anticonvulsants and hepatoprotectors allowed to create an effective treatment complex to alleviate this drug pathology. Pharmacoeconomic research was based on organizational and legal, clinical and pharmacological standards. Dosage forms of drugs according to medicinal purposes have been established in pharmacotherapeutic regimens for the relief of drunken forms of alcoholic dependence (tablets occupy 23.1% of appointments, solutions – 76.9%). The results of ABC analysis were given. Category A included seven INNs of drugs, the share of which was 81.13% of the total cost of pharmacotherapy of alcoholic dependence. Category B included four INNs of drugs with a cost share of 15.07%. In the category of C – two INNs of drugs with a share of costs of 4.80% for pharmacotherapy of relief of drunken states of alcoholic dependence. Overall, 85% of the studied drugs were included in pharmacotherapy as Vital, 15% as Essential. The results of the study can be used in conducting of budget tenders for the purchase of drugs, the rational use of drugs, the inclusion of drugs in regional and local forms for pharmacotherapy for the relief of drunken forms of drugs in healthcare facilities.

Abstract. An integrated ABC/VEN analysis of drug prescriptions in pharmacotherapeutic schemes for the relief of alcoholic dependence was performed. A retrospective analysis of seventy-five anonymized case histories of patients who sought medical help with drunken forms of alcoholic dependence was processed. The scheme of basic pharmacotherapy of relief of drunken forms of alcoholic dependence, developed by associate professor Yurii Chuiev for carrying out interdisciplinary study was used. Substantiated that the introduction of the developed innovative treatment algorithm, with the use of laser therapy, infusion therapy, anticonvulsants and hepatoprotectors allowed to create an effective treatment complex to alleviate this drug pathology. Pharmacoeconomic research was based on organizational and legal, clinical and pharmacological standards. Dosage forms of drugs according to medicinal purposes have been established in pharmacotherapeutic regimens for the relief of drunken forms of alcoholic dependence (tablets occupy 23.1% of appointments, solutions -76.9%). The results of ABC analysis were given. Category A included seven INNs of drugs, the share of which was 81.13% of the total cost of pharmacotherapy of alcoholic dependence. Category B included four INNs of drugs with a cost share of 15.07%. In the category of Ctwo INNs of drugs with a share of costs of 4.80% for pharmacotherapy of relief of drunken states of alcoholic dependence. Overall, 85% of the studied drugs were included in pharmacotherapy as Vital, 15% as Essential. The results of the study can be used in conducting of budget tenders for the purchase of drugs, the rational use of drugs, the inclusion of drugs in regional and local forms for pharmacotherapy for the relief of drunken forms of drugs in healthcare facilities. Keywords: psychoactive substances, alcohol dependence, pharmacotherapy, pharmacoeconomics, ABC/VEN analysis, drugs.
Introduction. COVID-19 has led to an unprecedented pandemic that has affected deaths worldwide. In the context of the COVID-19 pandemic, timely pharmacotherapy to alleviate the intoxication of alcohol dependence (AD) will significantly improve the condition and quality of life of such a group of patients.
Despite numerous publications on COVID-19, the conceptual understanding of the problem is still in its infancy. New public health data in the UK suggest that vaccination against COVID-19 has a positive effect in preventing symptomatic disorders among most patients with comorbidities compared to the rest of the population [1][2][3][4][5].
Pharmacotherapy of patients with intoxicated forms of AD is one of the most pressing issues of medical care during the COVID-19 pandemic. About 50% of patients with AD and coronavirus disease in the postpartum period suffer from withdrawal syndrome. Some foreign authors point to the need to integrate prescriptions into pharmacotherapeutic regimens for the relief of intoxicated forms of AD into an expanded rehabilitation program, supporting lifestyle changes. White fever, which occurs 2-3 days after withdrawal, is characterized by severe tremor, hallucinations and confusion, leading to death in 4% of hospitalized patients. Therefore, for such conditions it is necessary to use emergency medical care [6].
Today it is important to use modern, effective and safe drugs for  (Table 1).   (Table 2).   The distribution according to the results of VEN-analysis of the studied INNs of drugs for pharmacotherapy of relief of drunken forms of AD shown on the Fig. 1.  The results of the study can be used in conducting budget tenders for the purchase of drugs, the rational use of drugs, the inclusion of drugs in regional and local forms for pharmacotherapy for the relief of drunken forms of drugs in health care facilities.
Conclusions. An integrated ABC/VEN analysis of drug prescriptions in pharmacotherapeutic schemes for the relief of drunken forms of AD was performed.